Diabetic Cardiomyopathy

Diabetic Cardiomyopathy

Please use recent reference as much as you can

– Diabetic cardiomyopathy

-Definition and introduction

-Incidence

-Diagnosis

-Pathophysiology

*Inflammation and AGEs

*Mitochondrial dysfunction and ER stress

*Apoptosis

* Oxidative Stress

*Lipotoxicity and fatty acid utilization

*Fibrosis

*Renin

-Angiotensin

-Aldosterone System

– Treatment option and guideline

– LCZ696 (Valsartan/sacubitril ) as a promising drug of choice